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From conventional towards new – natural surfactants in drug delivery systems design: current status and perspectives

Savić, Snezana and Tamburic, Slobodanka and Savić, Miroslav (2010) From conventional towards new – natural surfactants in drug delivery systems design: current status and perspectives. Expert Opinion on Drug Delivery, 7 (3). pp. 353-369. ISSN 1742-5247 [Physical Sciences > Cosmetic Science]
Creators:Savić, Snezana and Tamburic, Slobodanka and Savić, Miroslav

Importance of the field: Surfactants play an important role in the development of both conventional and advanced (colloidal) drug delivery systems. There are several commercial surfactants, but a proportionally small group of them is approved as pharmaceutical excipients, recognized in various pharmacopoeias and therefore widely accepted by the pharmaceutical industry.

Areas covered in this review: The review covers some of the main categories of natural, sugar-based surfactants (alkyl polyglucosides and sugar esters) as prospective pharmaceutical excipients. It provides analysis of the physicochemical characteristics of sugar-based surfactants and their possible roles in the design of conventional or advanced drug delivery systems for different routes of administration.

What the reader will gain: Summary and analysis of recent data on functionality, applied concentrations and formulation improvements produced by alkyl polyglucosides and sugar esters in different conventional and advanced delivery systems could be of interest to researchers dealing with drug formulation.

Take home message: Recent FDA certification of an alkyl polyglucoside surfactant for topical formulation presents a significant step in the process of recognition of this relatively new group of surfactants. This could trigger further research into the potential benefits of naturally derived materials in both conventional and new drug delivery systems.

Official Website:http://dx.doi.org/10.1517/17425240903535833
Type of Research:Article
Your affiliations with UAL:Colleges > London College of Fashion
Colleges > London College of Fashion
Date:March 2010
Digital Object Identifier:10.1517/17425240903535833
Projects or Series:Research Outputs Review (April 2010 - April 2011)
ID Code:4122
Deposited On:31 May 2011 15:09
Last Modified:20 Mar 2014 12:22
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