Enhancing the topical delivery of N-acetyl-D-glucosamine: screening emulsifying systems

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Tamburic, Slobodanka and Baltazar, Diogo and Lim, Jasmine and Rodrigues, Sofia and Marto, Joana and Rei, Catarina and Stevic, Milica and Ribeiro, Helena Margarida (2018) Enhancing the topical delivery of N-acetyl-D-glucosamine: screening emulsifying systems. In: 30th IFSCC Congress, 18 - 21 Sept 2018, Munich, Germany.

Type of Research:	Conference, Symposium or Workshop Item
Creators:	Tamburic, Slobodanka and Baltazar, Diogo and Lim, Jasmine and Rodrigues, Sofia and Marto, Joana and Rei, Catarina and Stevic, Milica and Ribeiro, Helena Margarida
Description:	N-acetyl-D-glucosamine (GlcNAc) is a hydrophilic compound (log P = –2.1) and a versatile topical active. A monomer of hyaluronan (HA), it shares many of its physiological effects: it improves skin hydration, promotes the production of collagen and HA by fibroblasts and, as a tyrosinase inhibitor, also reduces hyperpigmentation [1–3]. However, contrary to HA, GlcNAc has a low molecular weight (221.21 g.mol-1), which makes it a suitable compound to permeate the skin. Amphiphilic emulsifiers are used to stabilise emulsions, yet there is limited information about their influence on skin delivery [4]. This study explored the influence of different emulsifiers in optimising the topical delivery of GlcNAc.
Official Website:	https://ifscc2018.com/
Keywords/subjects not otherwise listed:	cosmetic science
Your affiliations with UAL:	Colleges > London College of Fashion
Date:	20 September 2018
Event Location:	Munich, Germany
Date Deposited:	13 Dec 2018 09:50
Last Modified:	12 Mar 2019 12:43
Item ID:	13686
URI:	https://ualresearchonline.arts.ac.uk/id/eprint/13686

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